Epidemiological study of Functional Dry Eye Disease in Working-class Population in Shanghai, China
Parole chiave:
Functional dry eye disease, questionnaire, risk factor, contact lens, deep sleepAbstract
Background: To investigate the current status, morbidity, and risk factors of functional dry eye disease (DED) in Shanghai's working-class population and explore measures to fundamentally cure and prevent functional DED. Methods: A questionnaire form was used to record the data of the diagnosed functional DED working-class subjects in Shanghai, the results were recorded and analyzed. Additionally, the subjective symptoms of DED subjects and the respective clinical results were also recorded. The classification and corneal staining between subjects who wear contact lens or without were compared. The correlation of classification and corneal staining with their risk factors were also analyzed. Results: The risk factors of functional DED showed much in common though their works have professional particularity. Evaporative dry eye (EDE) accounts for a large proportion of DED (45.35%), many subjects co-exist symptoms and signs of mixed DED (32.64%). The age of 21-40 is the peak year range (70.4%). Contact lens, visual terminals, air-conditioner, decoration, stay up later, sleep disorder, smoking were risk factors in most functional DED subjects. Notably, contact lens is a leading risk factor to cause functional DED and ocular surface complications (both were p<0.01), while deep sleep seems to be a protective factor (p<0.01%). Conclusion: The incidence of functional DED in Shanghai is kept in a high level. Most risk factors are closely related to daily work and life, while they are almost reversible. Exploring and eradicating these daily risk factors seems to be a more preferable way to fundamentally control and prevent functional DED.
Riferimenti bibliografici
Craig JP, Nichols KK, Akpek EK, et al. TFOS DEWS II Definition and Classification Report. Ocul Surf. 2017;15(3):276-283. Doi: 10.1016/j.jtos.2017.05.008.
Pflugfelder, S.C. Management and therapy of dry eye disease: report of the Management and
Therapy Subcommittee of the International Dry Eye WorkShop. Ocul Surf. 2007;5(2): 163-178. Doi: 10.1016/s1542-0124(12)70085-x
Dana R, Bradley JL, Guerin A, et al. Estimated Prevalence and Incidence of Dry Eye Disease Based on Coding Analysis of a Large, All-age United States Health Care System. Am J Ophthalmol. 2019; 202:47-54. Doi: 10.1016/j.ajo.2019.01.026.
Cai Y, Wei J, Zhou J, et al. Prevalence and Incidence of Dry Eye Disease in Asia: A Systematic Review and Meta-Analysis. Ophthalmic Res. 2022;65(6):647-658. Doi: 10.1159/000525696
Lienert JP, Tarko L, Uchino M, et al. Long-term Natural History of Dry Eye Disease from the Patient's Perspective. Ophthalmology. 2016;123(2):425-433. Doi: 10.1016/j.ophtha. 2015.10. 011
Liang LY, Li J, Liu ZG. Focusing on the functional dry eye. Zhonghua Yan Ke Za Zhi. 2019; 55(12):885-890. Doi: 10.3760/cma.j.issn.0412-4081.2019.12.003
Van Tilborg MM, Murphy PJ, Evans KS. Impact of dry eye symptoms and daily activities in a
modern office. Optom Vis Sci. 2017;94(6):688-693. Doi: 10.1097/OPX.0000000000001086
Kawashima M, Sano K, Takechi S, et al. Impact of lifestyle intervention on dry eye disease in office workers: a randomized controlled trial. J Occup Health. 2018;60(4):281-188. Doi: 10.1539/joh.2017-0191-OA
Bazeer S, Jansonius N, Snieder H, et al. The relationship between occupation and dry eye. Ocul Surf. 2019;17(3):484-490. Doi: 10.1016/j.jtos.2019.04.004
Wolffsohn JS, Arita R, Chalmers R, et al. TFOS DEWS II Diagnostic Methodology report. Ocul Surf. 2017;15(3): 539-74. Doi: 10.1016/j.jtos.2017.05.001
McMonnies CW. Eye rubbing type and prevalence including contact lens 'removal-relief' rubbing. Clin Exp Optom. 2016; 99(4):366-372. Doi: 10.1111/cxo.12343
Dogan AS, Gurdal C, Arslan N. Corneal confocal microscopy and dry eye findings in contact
lens discomfort patients. Cont Lens Anterior Eye. 2018;41(1):101-104. Doi: 10.1016/j.clae. 2017.08.001
Li W, Sun X, Wang Z, et al. A survey of contact lens-related complications in a tertiary hospital in China. Cont Lens Anterior Eye. 2018;41(2):201-204. Doi: 10.1016/j.clae.2017.10.007
Guillon M, Dumbleton KA, Theodoratos P, et al. Association between contact lens discomfort and pre-lens tear film kinetics. Optom Vis Sci. 2016;93(8):881-891. Doi: 10.1097/OPX. 0000000000000866
Hall, A. J. Some observations on the acts of closing and opening the eyes. Br J Ophthalmol.
; 20(5):257-295. Doi: 10.1136/bjo.20.5.257
Yu X, Guo H, Liu X, et al. Dry eye and sleep quality: a large community-based study in Hangzhou. Sleep. 2019;42(11):zsz160. Doi: 10.1093/sleep/zsz160
Ayaki M, Tsubota K, Kawashima M, et al. Sleep Disorders are a Prevalent and Serious Comorbidity in Dry Eye. Invest Ophthalmol Vis Sci. 2018;59(14): DES143-150. Doi: 10.1167/ iovs.17-23467
Li S, Ning K, Zhou J, et al. Sleep deprivation disrupts the lacrimal system and induces dry eye disease. Exp Mol Med. 2018;50(3):e451. Doi: 10.1038/emm.2017.285
Li S, Tang L, Zhou J, et al. Sleep deprivation induces corneal epithelial progenitor cell over-expansion through disruption of redox homeostasis in the tear film. Stem Cell Reports. 2022. 10;17(6):1105-1119. Doi: 10.1016/j.stemcr.2022.05.007
Gipson IK, Argueso P. Role of mucins in the function of the corneal and conjunctival epithelia. Int Rev Cytol. 2013;231:1–49. Doi: 10.1016/s0074-7696(03)31001-0
Jester JV, Potma E, Brown DJ. PPARγ Regulates Mouse Meibocyte Differentiation and Lipid
Synthesis. Ocul Surf. 2016;14(4):484-494. Doi: 10.1016/j.jtos.2016.08.001
Tang L, Wang X, Wu J, et al. Sleep deprivation induces dry eye through inhibition of PPARα expression in corneal epithelium. Invest Ophthalmol Vis Sci. 2018;59(13): 5494-5508. Doi: 10.1167/iovs.18-24504
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