Histopathologic overlap between fibrotic sarcoidosis and UIP pattern
Keywords:
Fibrotic sarcoidosis, UIP, honeycombing, cryobiopsyAbstract
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References
1. Patterson KC, Strek ME. Pulmonary fibrosis in sarcoidosis: clinical features and outcomes. Ann Am Thorac Soc. 2013;10(4):362–70. doi:10.1513/AnnalsATS.201303-069FR.
2. Łyżwa E, Wakuliński J, Szturmowicz M, et al. Fibrotic pulmonary sarcoidosis: from pathogenesis to management. J Clin Med. 2025;14(7):2381. doi:10.3390/jcm14072381.
3. Bandyopadhyay D, Mirsaeidi MS. Sarcoidosis-associated pulmonary fibrosis: joining the dots. Eur Respir Rev. 2023;32(169):230085. doi:10.1183/16000617.0085-2023.
4. Verleden SE, Vanstapel A, De Sadeleer L, et al. Distinct airway involvement in subtypes of end-stage fibrotic pulmonary sarcoidosis. Chest. 2021;160(2):562–71. doi:10.1016/j.chest.2021.01.003.
5. Obi ON, Alqalyoobi S, Maddipati V, et al. High-resolution CT scan fibrotic patterns in stage IV pulmonary sarcoidosis: impact on pulmonary function and survival. Chest. 2024;165(4):892–907. doi:10.1016/j.chest.2023.10.021.
6. Desai SR, Sivarasan N, Johannson KA, et al. High-resolution CT phenotypes in pulmonary sarcoidosis: a multinational Delphi consensus study. Lancet Respir Med. 2024;12(5):409–18. doi:10.1016/S2213-2600(23)00267-9.
7. Kawanobe T, Yamaguchi T, Ishida Y, et al. Fibrotic pulmonary sarcoidosis with honeycomb-like changes mimicking idiopathic pulmonary fibrosis/usual interstitial pneumonia (IPF/UIP) in the lower lobes: a case treated with anti-fibrotic therapy. Intern Med. 2026;65(3):474–8. doi:10.2169/internalmedicine.5537-25.
8. Zhang C, Chan KM, Schmidt LA, et al. Histopathology of explanted lungs from patients with a diagnosis of pulmonary sarcoidosis. Chest. 2016;149(2):499–507. doi:10.1378/chest.15-0615.
9. Churg A, Poletti V, Ravaglia C, et al. Pathological features of connective tissue disease-associated interstitial lung disease in transbronchial cryobiopsies. Histopathology. 2025;86(2):260–7. doi:10.1111/his.15311.
10. Chilosi M, Piciucchi S, Ravaglia C, et al. "Alveolar stem cell exhaustion, fibrosis and bronchiolar proliferation" related entities: a narrative review. Pulmonology. 2025;31(1):2416847. doi:10.1016/j.pulmoe.2024.05.005.
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Copyright (c) 2026 Wai Ling Leong, Venerino Poletti, Claudia Ravaglia, Sara Piciucchi

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