Breaking the odds: A rare case of bilateral breast angiosarcoma

Breaking the odds: A rare case of bilateral breast angiosarcoma

Authors

  • Sara Maria Pizzileo Department of Clinical and Experimental Medicine, Foggia University School of Medicine, University of Foggia, Foggia, Italy https://orcid.org/0009-0001-9554-4742
  • Francesco Pizzolorusso Department of Clinical and Experimental Medicine, Foggia University School of Medicine, University of Foggia, Foggia, Italy. https://orcid.org/0009-0006-1601-8573
  • Angelo Errico Department of Radiation Oncology, "Mons. Dimiccoli Hospital", Barletta (BT), Italy
  • Giulia Iacobellis Department of Clinical and Experimental Medicine, Foggia University School of Medicine, University of Foggia, Foggia, Italy. https://orcid.org/0009-0007-8972-7837
  • Annalisa Lamacchia Department of Radiation Oncology, "Mons. Dimiccoli Hospital", Barletta (BT), Italy
  • Stefano De Lorenzis Department of Clinical and Experimental Medicine, Foggia University School of Medicine, University of Foggia, Foggia, Italy. https://orcid.org/0009-0007-7429-0126
  • Santa Bambace Department of Radiation Oncology, "Mons. Dimiccoli Hospital", Barletta (BT), Italy
  • Giuseppe Guglielmi Department of Clinical and Experimental Medicine, Foggia University School of Medicine, University of Foggia, Foggia, Italy; Radiology Unit, Barletta University Hospital, Italy.

Keywords:

Breast Angiosarcoma, Breast MRI, Radiation Therapy, Soft tissues, Breast Oncology, Diagnostic Challenges

Abstract

Breast angiosarcoma is an extremely rare and aggressive tumor, presenting several challenges in diagnosis and treatment. Imaging techniques play a crucial role in the early diagnostic assessment, initially allowing for a differential diagnosis with other breast tumors (using ultrasound and MRI techniques) and subsequently for patient follow-up through CT and MRI examinations.

Currently, there is no standardized or unified treatment protocol, especially regarding metastatic forms, where the use of chemotherapy or radiotherapy remains subject of debate.

The rarity of this tumor entity suggests the need for future research and multidisciplinary collaboration in order to further optimize diagnostic accuracy and treatment options.

References

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Published

05-08-2025

Issue

Section

CASE REPORTS

How to Cite

1.
Pizzileo SM, Pizzolorusso F, Errico A, et al. Breaking the odds: A rare case of bilateral breast angiosarcoma. Acta Biomed. 2025;96(4):16881. doi:10.23750/abm.v96i4.16881